Te nama Cas Florfenicol: 73231-34-2 Tātai rāpoi: C12H14Cl2FNO4S
2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
AQUAFEN FLORFENICOL NUFLOR
[r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
SCH-25298
(r-(r*,s*))-methyleste
2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-benzenesulfonicaci
Ko Florfeniol
FLUPROFEN
Fluorothiamphenicol
Sch-25298, Aquafen
Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
Aquaflor
Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl ] acetamide
2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
| Te Whakarewa | 153 ° |
| Kiato | 1.451±0.06 g/cm3(I Matapae)1.1782(whakatau tata) |
| pāmahana rokiroki | 2-8°C |
| whakarewatanga | Wairewa ki te waihā ki te 25mM me te DMSO ki te100mM |
| mahi whatu | N/A |
| Te ahua | Ma ki Off-White |
| Maamaa | ≥98% |
Ko te Florfenicol he paturopi fluorinated whanui whanui me te whakaputanga o te thiamphenicol (Tuemi Nama 21357).He kaha ki te aukati i nga momo haumanu tangata o te huakita enteric, tae atu ki te E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, me Salmonella (MIC).50s = 6.3-12.5 μg/ml).Kei te kaha ano a Florfenicol ki te patu i nga momo mate pukupuku o nga momo mate pukupuku o te bovine me te porcine, tae atu ki te P. multocida, te A. pleuropneumoniae, me te B. bronchiseptica (MIC).50s = 0.25-4 μg/ml).Ka whakakorehia te mahi peptidyl transferase i roto i nga ribosomes 70S kua wehea mai i te E. coli ka whakamahia i te kukū o te 1 mM.Kua whakamahia nga rongoa kei roto te florfenicol ki te rongoa i nga mate rewharewha i roto i nga kararehe.
He momo rongoa paturopi.Ka whakamahia hei rongoa mo te rongoa kararehe mo te rongoa i nga mate kitakita o te poaka, heihei me te ika.He pai te kaha ki te rongoa i nga mate o te poaka, te heihei me te ika na te huakita tairongo, ina koa mo te rongoa i nga mate manawa me nga mate whekau.
