Te nama cas: 21187-98-4 Tātai Molecular

Whakaahuatanga Poto:

Te nama cas: 21187-98-4

Ingoa matū:

Tātai rāpoi:C15H21N3O3S

Kupu taurite:BP;)-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h )-yl)-3-(p-tolylsulfonyl)-ure;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea;benzenesulfonamide,n-(((hexahydrocyclopenta() c)pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n'-(3-azabicyclo(3.3.0)oct-3-yl)urea;Tetrabenzyl Voglibose HCl

Tukuna he imeera ki a matou

Taipitopito Hua

Tohu Hua

Whakatakotoranga Hua

Te Whakarewa	163-169 °C
Kiato	1.2205 (whakatau tata)
pāmahana rokiroki	Te hau hau, Te Pamahana rūma 2-8°C
whakarewatanga	methylene pūhaumāota: wairewa
mahi whatu	N/A
Te ahua	Mārō-Ma
Maamaa	≥98%

Whakaahuatanga

he kaihoko antihyperglycemic waha e whakamahia ana mo te maimoatanga o te mate huka mellitus momo II.No te karaehe sulfonylurea o te insulin secretagogues, e whakaihiihi ana i nga pūtau β o te pancreas ki te tuku i te insulin.ka herea ki te β cell sulfonyl urea receptor (SUR1), ka aukati ano i nga waahana pāhare pāporo tairongo ATP.Na reira, ka tino heke te toha o te pāhare pāporo, ka mutu te whakahekenga o nga pūtau β.Na ka tuwhera nga hongere konupūmā e whakawhirinaki ana ki te ngaohiko i roto i te pūtau β, ka puta te whakahohenga calmodulin, ka puta ki te exocytosis o te insulin kei roto nga granules secretorty.Kua whakaatuhia ano e nga rangahau tata nei ka taea te whakapai ake i te mana anti-oxidant me te vasodilation-waikura-waikura i roto i te mate huka Momo 2 me te tiaki i nga pūtau beta pancreatic mai i te kino o te hauwai peroxide.

te whakamahinga me te inenga

he kaihoko hypoglycemic a-waha e whakamahia ana ki te rongoa i te mate huka-kore-whakaaro ki te insulin.Te maimoatanga o te mate huka e pa ana ki te momona, ki te mate ngongo ranei, mo nga pakeke e mate ana i te mate huka momo 2. Ko te mate huka he mate hauora roa (roa) e pa ana ki te hurihanga o to tinana. kai ki te kaha.ka whakaheke i nga taumata huka toto ma te whakaihiihi i te hunanga o te insulin mai i nga pūtau β o nga moutere o Langerhans.