Te nama cas: 330784-47-9 Tātai rāpoi: C23H26ClN7O3

Whakaahuatanga Poto:

Te nama cas: 330784-47-9

Ingoa matū:

Tātai rāpoi:C23H26ClN7O3

Nga kupu taurite:(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine

4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide

Tukuna he imeera ki a matou

Taipitopito Hua

Tohu Hua

Whakatakotoranga Hua

Te Whakarewa	150-152°C
Kiato	1.372
pāmahana rokiroki	Kua hiri ki te maroke, Rokiroki i roto i te pouaka tio, i raro i te -20°C
whakarewatanga	DMSO (Paku), Methanol (Paku, Wehana)
mahi whatu	N/A
Te ahua	Ma ki Off-White
Maamaa	≥98%

pharmacodynamics

(Zepeed) i whakaaetia e te Korean Health Ministry mo te maimoatanga o te erectile dysfunction (ED) i te marama o Akuhata 2011.he momo tino whiriwhiri 5 phosphodiesterase (PDE5) inhibitor.e kiia ana ko te aukati PDE5 tino whiriwhiri i runga i te maakete.He rereke ano te tiimata o te Tmax me te haurua o te ora i waenga i nga aukati PDE5 kua hokona.Kei a Sildenafil he T_mōrahii te 1 haora me te haurua o te 3-5 haora.Ko Vardenafil he ahua rite ki te T_mōrahio 0.6 haora me te haurua o te ora o te 4-6 haora.Ko Tadalafil te roa o te haurua o te ora i waenga i nga raau taero hokohoko me te hawhe-ora o te 17 h.he tere te mahi ka tae ki T_mōrahii roto i te 0.6 h me te haurua o te 1.2 h.Ko te whakahiato o (TA-1790) e whakaahuatia ana i roto i nga tuhinga patent.Ko te huarahi tino nui o te whakakorenga ko te ma te papa me te feces.i kitea ano ka hoki mai ano na roto i te recirculation enterohepatic.