Rifampicin Cas nama:13292-46-1 Tātai Molecular: C43H58N4O12 Atahanga Whakaatu

Rifampicin Nama cas:13292-46-1 Tātai Molecular: C43H58N4O12

Whakaahuatanga Poto:

Tātai rāpoi:
C43H58N4O12

Kupu taurite:9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2-h)-dione,5,6;3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-((4-methyl-1-piperazinyl)iminomethyl )rifamycinsv;8-(((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv;8-(4-Methylpiperazinyliminomethyl)rifamycinSV;8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins; RIFAMPIN "LEPETIT"

Tukuna he imeera ki a matou

Taipitopito Hua

Tohu Hua

Whakatakotoranga Hua

Te Whakarewa	183 °
Kiato	1.1782(whakatau tata)
pāmahana rokiroki	2-8°C
whakarewatanga	chloroform: whakarewa50mg/mL, maamaa
mahi whatu	N/A
Te ahua	he whero iti ki te whero tino pouri
Maamaa	≥99%

Whakaahuatanga

Ko te Rifampicin he huanga o te rifamicin B, he paturopi macrolactam me tetahi o nga paturopi neke atu i te rima mai i te ranunga o rifamicins A, B, C, D, me E, e kiia nei ko te rifamicin complex, he mea hanga e actinomycetes Streptomyces mediteranei ( Nocardia mediteranei).I whakauruhia ki roto i nga mahi rongoa i te tau 1968. Ka timata te whakahiatotanga o te rifampicin ki te wairewa wai o te rifamicin, i raro i nga tikanga tauhohenga ka oxidized ki te pärönaki hou o rifamicin S (32.7.4), me te hanganga takawaenga o rifamicin O (32.7. 3).Ko te whakaheke i te hanganga kuinione o tenei hua me te hauwai ma te whakamahi i te palladium i runga i te whakakorikori waro ka hoatu te rifamicin SV (32.7.5).Ko te hua ka puta ko te aminomethylation ma te ranunga o te formaldehyde me te pyrrolidine, ka hoatu te 3-pyrrolidinomethylrifamicin SV (32.7.6).Ko te whakapouri i te hua ka puta me te tetracetate mata ki te enamine me te hauwai o muri mai me te wairewa wai o te waikawa ascorbic ka hoatu te 3-formylrifamicin SV (32.7.7).Ko te whakautu i tenei me te 1-amino-4-methylpiperazine ka homai te rifampicin e hiahiatia ana (32.7.8).

te whakamahinga me te inenga

Ka whakamahia te Rifampin hei paturopi.He pärönaki hangarua o te rifamycin B, he paturopi macrocyclic i hangaia e te koriri Streptomyces mediterranei.Ka whakamahia te Rifampin mo te maimoatanga o te mate kohi, brucellosis, Staphlococcus aureus, me etahi atu mate hopuhopu.